Behavioral Phenotype of Cognition and Language in Down Syndrome
Down syndrome, arising from trisomy of chromosome 21 and the subsequent cascade of genetic effects and physical sequelae (Lott & McCoy, 1992), exerts a phenotypically distinct influence on a child’s cognitive and language development (Abbeduto et al., 2001; Chapman & Hesketh, 2000; Miller, 1995). Down syndrome is typically accompanied by mild to moderate delays in the development of nonverbal cognitive skills and additional deficits in short-term memory, with a greater deficit in the short-term memory of …
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